
GLP-1 Weight Loss Drugs: How They Work, Results and Risks
Semaglutide and tirzepatide explained: mechanism, real weight loss numbers from the STEP and SURMOUNT trials, side effects, muscle loss, weight regain after stopping, and who they are for.
7 articles

Semaglutide and tirzepatide explained: mechanism, real weight loss numbers from the STEP and SURMOUNT trials, side effects, muscle loss, weight regain after stopping, and who they are for.

Why weight loss stalls: water retention, metabolic adaptation, falling NEAT and portion creep. Real numbers on adaptation, plus a fix-it order that works.

What your daily energy burn is really made of, why metabolism does not crash at 30, and which levers — muscle, NEAT, protein, sleep — actually move the number.

The glycemic index is measured on a 50 g carbohydrate portion, which is why it misleads. How GI is tested, why glycemic load is better, and who benefits.

Where BMI came from, when it works and when it fails, why waist-to-height ratio beats it, and how to read your body composition without expensive equipment.

How to work out your maintenance calories, what size of deficit is safe, why tracked deficits often fail to move the scale, and the habits that hold.

What randomised trials actually show about 16:8, 5:2 and alternate-day fasting, the muscle-loss problem, the truth about autophagy, and who should avoid it.