Autophagy and Fasting: What Is Proven and What Is Hype
What autophagy is, whether fasting really 'cleans your cells' and extends life, and why most of the loud claims about autophagy are not yet proven in humans.
10 articles
What autophagy is, whether fasting really 'cleans your cells' and extends life, and why most of the loud claims about autophagy are not yet proven in humans.
What NAD+ is and why it declines with age, what the studies of NMN and NR supplements actually showed, and whether they are worth paying for in the name of longevity.

Why the 'glass of wine is good for you' finding turned out to be a study artefact, what WHO and Mendelian randomisation show, how alcohol affects the heart, brain, liver and cancer risk.

Sarcopenia is a coded diagnosis, not ordinary ageing. How to screen yourself in five minutes, why strength beats mass, and the two things that actually work.

Epigenetic clocks are a genuine scientific advance, but consumer tests have a reliability problem: rerunning the same sample can shift the answer by years.

The most studied eating pattern in the world: the PREDIMED evidence, what the diet contains, a weekly framework, and how to adapt it to an ordinary supermarket and budget.

Finnish cohorts link frequent sauna use to lower heart and all-cause mortality. We cover the mechanisms, safety, and the limits of the evidence.

A decade-by-decade guide to screening that earns its place, based on USPSTF grades, plus the popular tests that do more harm than good in healthy adults.

What VO2max measures, how it tracks mortality in 122,007 adults, reference values by age and sex, how to test it, and how much you can realistically raise it.

A careful look at the Blue Zones: the record-keeping problem Saul Newman uncovered, the branding around it, and which famous habits have real evidence.